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Complex splicing pattern generates great diversity in human NF1 transcripts

BACKGROUND: Mutation analysis of the neurofibromatosis type 1 (NF1) gene has shown that about 30% of NF1 patients carry a splice mutation resulting in the production of one or several shortened transcripts. Some of these transcripts were also found in fresh lymphocytes of healthy individuals, albeit...

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Hlavní autoři: Vandenbroucke, Ina, Callens, Tom, De Paepe, Anne, Messiaen, Ludwine
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC115845/
https://ncbi.nlm.nih.gov/pubmed/12057013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-3-13
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