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Persistent organ dysfunction plus death: a novel, composite outcome measure for critical care trials

INTRODUCTION: Due to resource limitations, few critical care interventions have been rigorously evaluated with adequately powered randomized clinical trials (RCTs). There is a need to improve the efficiency of RCTs in critical care so that more definitive high quality RCTs can be completed with the...

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Autori principali: Heyland, Daren K, Muscedere, John, Drover, John, Jiang, Xuran, Day, Andrew G
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219367/
https://ncbi.nlm.nih.gov/pubmed/21418560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10110
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