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Splitting the task: Ubp8 and Ubp10 deubiquitinate different cellular pools of H2BK123

Monoubiquitination of H2BK123 (H2BK123ub), catalyzed by Rad6/Bre1, is a transient histone modification with roles in transcription and is essential for establishing H3K4 and H3K79 trimethylations (H3K4me3 and H3K79me3). Here, we investigated the chromatin network around H2BK123ub by examining its lo...

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Sonraí Bibleagrafaíochta
Main Authors: Schulze, Julia M., Hentrich, Thomas, Nakanishi, Shima, Gupta, Arvind, Emberly, Eldon, Shilatifard, Ali, Kobor, Michael S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219228/
https://ncbi.nlm.nih.gov/pubmed/22056669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.177220.111
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