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Synergy between inhibitors of androgen receptor and MEK has therapeutic implications in estrogen receptor-negative breast cancer

INTRODUCTION: Estrogen receptor-negative (ER-) breast cancer is a heterogeneous disease with limited therapeutic options. The molecular apocrine subtype constitutes 50% of ER-tumors and is characterized by overexpression of steroid response genes including androgen receptor (AR). We have recently id...

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Detalles Bibliográficos
Main Authors: Naderi, Ali, Chia, Kee Ming, Liu, Ji
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219199/
https://ncbi.nlm.nih.gov/pubmed/21457548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2858
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