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Isotretinoin and FoxO1: A scientific hypothesis

Oral isotretinoin (13-cis retinoic acid) is the most effective drug in the treatment of acne and restores all major pathogenetic factors of acne vulgaris. isotretinoin is regarded as a prodrug which after isomerizisation to all-trans-retinoic acid (ATRA) induces apoptosis in cells cultured from huma...

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Bibliografiske detaljer
Hovedforfatter: Melnik, Bodo C
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219165/
https://ncbi.nlm.nih.gov/pubmed/22110774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/derm.3.3.15331
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