Copy number variation detection in whole-genome sequencing data using the Bayesian information criterion

DNA copy number variations (CNVs) play an important role in the pathogenesis and progression of cancer and confer susceptibility to a variety of human disorders. Array comparative genomic hybridization has been used widely to identify CNVs genome wide, but the next-generation sequencing technology p...

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Detalhes bibliográficos
Main Authors: Xi, Ruibin, Hadjipanayis, Angela G., Luquette, Lovelace J., Kim, Tae-Min, Lee, Eunjung, Zhang, Jianhua, Johnson, Mark D., Muzny, Donna M., Wheeler, David A., Gibbs, Richard A., Kucherlapati, Raju, Park, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219132/
https://ncbi.nlm.nih.gov/pubmed/22065754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110574108
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