Role of donor genital tract HIV-1 diversity in the transmission bottleneck

The predominant mode of HIV-1 infection is heterosexual transmission, where a genetic bottleneck is imposed on the virus quasispecies. To probe whether limited genetic diversity in the genital tract (GT) of the transmitting partner drives this bottleneck, viral envelope sequences from the blood and...

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Bibliografiske detaljer
Main Authors: Boeras, Debrah I., Hraber, Peter T., Hurlston, Mackenzie, Evans-Strickfaden, Tammy, Bhattacharya, Tanmoy, Giorgi, Elena E., Mulenga, Joseph, Karita, Etienne, Korber, Bette T., Allen, Susan, Hart, Clyde E., Derdeyn, Cynthia A., Hunter, Eric
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219102/
https://ncbi.nlm.nih.gov/pubmed/22065783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103764108
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