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Nonautonomous regulation of Drosophila midgut stem cell proliferation by the insulin-signaling pathway

Drosophila adult midgut intestinal stem cells (ISCs) maintain tissue homeostasis by producing progeny that replace dying enterocytes and enteroendocrine cells. ISCs adjust their rates of proliferation in response to enterocyte turnover through a positive feedback loop initiated by secreted enterocyt...

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Détails bibliographiques
Auteurs principaux: Choi, Na Hyun, Lucchetta, Elena, Ohlstein, Benjamin
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219098/
https://ncbi.nlm.nih.gov/pubmed/22049341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109348108
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