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Nonautonomous regulation of Drosophila midgut stem cell proliferation by the insulin-signaling pathway
Drosophila adult midgut intestinal stem cells (ISCs) maintain tissue homeostasis by producing progeny that replace dying enterocytes and enteroendocrine cells. ISCs adjust their rates of proliferation in response to enterocyte turnover through a positive feedback loop initiated by secreted enterocyt...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219098/ https://ncbi.nlm.nih.gov/pubmed/22049341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109348108 |
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