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The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60

The product of the CLU gene promotes or inhibits tumourigenesis in a context-dependent manner. It has been hypothesised that different CLU isoforms have different and even opposing biological functions, but this theory has not been experimentally validated. Here we show that molecules involved in su...

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Detalhes bibliográficos
Main Authors: Chaiwatanasirikul, K-A, Sala, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219095/
https://ncbi.nlm.nih.gov/pubmed/22012253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.99
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