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Cytokine-dependent and cytokine-independent roles for Mcl-1: genetic evidence for multiple mechanisms by which Mcl-1 promotes survival in primary T lymphocytes

Myeloid cell leukemia sequence-1 (Mcl-1) is a critical anti-apoptotic factor in T lymphocytes. However, in spite of the many pro-apoptotic proteins with proposed binding to Mcl-1, the specific interactions by which Mcl-1 regulates primary T-cell survival under different conditions have not been full...

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Detalhes bibliográficos
Main Authors: Dunkle, A, Dzhagalov, I, He, Y-W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219091/
https://ncbi.nlm.nih.gov/pubmed/21975296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.95
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