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Mitochondrial complex I and cell death: a semi-automatic shotgun model

Mitochondrial dysfunction often leads to cell death and disease. We can now draw correlations between the dysfunction of one of the most important mitochondrial enzymes, NADH:ubiquinone reductase or complex I, and its structural organization thanks to the recent advances in the X-ray structure of it...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gonzalez-Halphen, D, Ghelli, A, Iommarini, L, Carelli, V, Esposti, M D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219089/
https://ncbi.nlm.nih.gov/pubmed/22030538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.107
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