Analysis of tumor environmental response and oncogenic pathway activation identifies distinct basal and luminal features in HER2-related breast tumor subtypes

INTRODUCTION: Breast cancer heterogeneity occurs as a consequence of the dysregulation of numerous oncogenic pathways as well as many non-genetic factors, including tumor microenvironmental stresses such as hypoxia, lactic acidosis, and glucose deprivation. Although the importance of these non-genet...

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Bibliografiska uppgifter
Huvudupphovsmän: Gatza, Michael L, Kung, Hsiu-Ni, Blackwell, Kimberly L, Dewhirst, Mark W, Marks, Jeffrey R, Chi, Jen-Tsan
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218951/
https://ncbi.nlm.nih.gov/pubmed/21672245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2899
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