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From bone to breast and back - the bone cytokine RANKL and breast cancer
Receptor activator of nuclear factor-κB ligand (RANKL) plays a pivotal role in regulating bone homeostasis. Osteoporosis and malignant bone disease secondary to breast cancer are characterized by enhanced RANKL production and increased bone turnover. Thus, denosumab, a monoclonal antibody to RANKL,...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218926/ https://ncbi.nlm.nih.gov/pubmed/21635706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2842 |
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