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From bone to breast and back - the bone cytokine RANKL and breast cancer

Receptor activator of nuclear factor-κB ligand (RANKL) plays a pivotal role in regulating bone homeostasis. Osteoporosis and malignant bone disease secondary to breast cancer are characterized by enhanced RANKL production and increased bone turnover. Thus, denosumab, a monoclonal antibody to RANKL,...

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Autors principals: Hofbauer, Lorenz C, Rachner, Tilman D, Hamann, Christine
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218926/
https://ncbi.nlm.nih.gov/pubmed/21635706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2842
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