High recombination rates and hotspots in a Plasmodium falciparum genetic cross

BACKGROUND: The human malaria parasite Plasmodium falciparum survives pressures from the host immune system and antimalarial drugs by modifying its genome. Genetic recombination and nucleotide substitution are the two major mechanisms that the parasite employs to generate genome diversity. A better...

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Hlavní autoři: Jiang, Hongying, Li, Na, Gopalan, Vivek, Zilversmit, Martine M, Varma, Sudhir, Nagarajan, Vijayaraj, Li, Jian, Mu, Jianbing, Hayton, Karen, Henschen, Bruce, Yi, Ming, Stephens, Robert, McVean, Gilean, Awadalla, Philip, Wellems, Thomas E, Su, Xin-zhuan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218859/
https://ncbi.nlm.nih.gov/pubmed/21463505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-4-r33
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