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Effects of SU5416 and a vascular endothelial growth factor neutralizing antibody on wear debris-induced inflammatory osteolysis in a mouse model

BACKGROUND: The development of highly vascularized and inflammatory periprosthetic tissue characterizes the progress of aseptic loosening, a major complication of joint arthroplasty. Vascular endothelial growth factor (VEGF) is an important cell signaling protein involved in angiogenesis. The purpos...

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Detalhes bibliográficos
Main Authors: Ren, Weiping, Zhang, Renwen, Wu, Bin, Wooley, Paul H, Hawkins, Monica, Markel, David C
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218747/
https://ncbi.nlm.nih.gov/pubmed/22096367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S16232
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