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Context-dependent splicing regulation: Exon definition, co-occurring motif pairs and tissue specificity

Splicing is a crucial process in gene expression in higher organisms because: (1) most vertebrate genes contain introns; and (2) alternative splicing is primarily responsible for increasing proteomic complexity and functional diversity. Intron definition, the coordination across an intron, is a mand...

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Bibliographic Details
Main Authors: Ke, Shengdong, Chasin, Lawrence A
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218509/
https://ncbi.nlm.nih.gov/pubmed/21444999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.3.14458
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