Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer

Poor prognosis cancers, such as pancreatic cancer, represent inherent challenges for ceramide-based nanotherapeutics due to metabolic pathways which neutralize ceramide to less toxic or pro-oncogenic metabolites. We have recently developed a novel 80 nanometer diameter liposomal formulation that inc...

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Main Authors: Jiang, Yixing, DiVittore, Nicole A, Kaiser, James M, Shanmugavelandy, Sriram S, Fritz, Jennifer L, Heakal, Yasser, Tagaram, Hephzibah Rani S, Cheng, Hua, Cabot, Myles C, Staveley-O'Carroll, Kevin F, Tran, Melissa A, Fox, Todd E, Barth, Brian M, Kester, Mark
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2011
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218384/
https://ncbi.nlm.nih.gov/pubmed/21795855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.7.15971
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