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Screening and Optimization of Ligand Conjugates for Lysosomal Targeting

The use of lysosome-targeted liposomes may significantly improve the delivery of therapeutic enzymes and chaperones into lysosomes for the treatment of lysosomal storage disorders. The aim of this research was to synthesize new potentially lysosomotropic ligands on a base of Neutral Red and rhodamin...

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Autori principali: Meerovich, Igor, Koshkaryev, Alexander, Thekkedath, Ritesh, Torchilin, Vladimir P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218248/
https://ncbi.nlm.nih.gov/pubmed/21913714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200336j
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