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Screening and Optimization of Ligand Conjugates for Lysosomal Targeting

The use of lysosome-targeted liposomes may significantly improve the delivery of therapeutic enzymes and chaperones into lysosomes for the treatment of lysosomal storage disorders. The aim of this research was to synthesize new potentially lysosomotropic ligands on a base of Neutral Red and rhodamin...

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Detalhes bibliográficos
Main Authors: Meerovich, Igor, Koshkaryev, Alexander, Thekkedath, Ritesh, Torchilin, Vladimir P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218248/
https://ncbi.nlm.nih.gov/pubmed/21913714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200336j
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