Increased Expression of the Large GTPase Dynamin 2 Potentiates Metastatic Migration and Invasion of Pancreatic Ductal Carcinoma

Pancreatic ductal tumors invade local parenchyma and metastasize to distant organs. Src-mediated tyrosine kinase signaling pathways promote pancreatic ductal adenocarcinoma (PDAC) metastasis, though the molecular mechanisms supporting this invasive process are poorly understood and represent importa...

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Main Authors: Eppinga, Robbin D., Krueger, Eugene W., Weller, Shaun G., Zhang, Lizhi, Cao, Hong, McNiven, Mark A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218232/
https://ncbi.nlm.nih.gov/pubmed/21841817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.329
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