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α-ketoglutarate coordinates carbon and nitrogen utilization via Enzyme I inhibition

Microbes survive in a variety of nutrient environments by modulating their intracellular metabolism. Balanced growth requires coordinated uptake of carbon and nitrogen, the primary substrates for biomass production. The mechanisms that balance carbon and nitrogen uptake are, however, poorly understo...

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Detalhes bibliográficos
Main Authors: Doucette, Christopher D, Schwab, David J, Wingreen, Ned S, Rabinowitz, Joshua D
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218208/
https://ncbi.nlm.nih.gov/pubmed/22002719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.685
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