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Direct lineage conversion of terminally differentiated hepatocytes to functional neurons

Several recent studies showed that mouse and human fibroblasts can be directly reprogrammed to induced neuronal (iN) cells, bypassing a pluripotent intermediate state. However, fibroblasts represent heterogeneous mesenchymal progenitor cells that potentially contain neural crest lineages, and the ce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marro, Samuele, Pang, Zhiping P., Yang, Nan, Tsai, Miao-Chih, Qu, Kun, Chang, Howard Y., Südhof, Thomas C., Wernig, Marius
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218088/
https://ncbi.nlm.nih.gov/pubmed/21962918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.09.002
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