Potential Biomarkers in Mouse Myocardium of Doxorubicin-Induced Cardiomyopathy: A Metabonomic Method and Its Application

BACKGROUND: Doxorubicin (DOX) is one of the most potent antitumor agents available; however, its clinical use is limited because of the risk of severe cardiotoxicity. Though numerous studies have ascribed DOX cardiomyopathy to specific cellular pathways, the precise mechanism remains obscure. Sini d...

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Detalhes bibliográficos
Main Authors: Tan, Guangguo, Lou, Ziyang, Liao, Wenting, Zhu, Zhenyu, Dong, Xin, Zhang, Wei, Li, Wuhong, Chai, Yifeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218026/
https://ncbi.nlm.nih.gov/pubmed/22110719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027683
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