Molecular Modeling Study of Chiral Separation and Recognition Mechanism of β-Adrenergic Antagonists by Capillary Electrophoresis

Chiral separations of five β-adrenergic antagonists (propranolol, esmolol, atenolol, metoprolol, and bisoprolol) were studied by capillary electrophoresis using six cyclodextrins (CDs) as the chiral selectors. Carboxymethylated-β-cyclodextrin (CM-β-CD) exhibited a higher enantioselectivity power com...

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Main Authors: Yifeng Chai, Zhenyu Zhu, Xinrong Zhang, Guangguo Tan, Wuhong Li, Changhai Liu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2012-01-01
Colecção:International Journal of Molecular Sciences
Assuntos:
molecular docking
cyclodextrin
β-adrenergic antagonists
capillary electrophoresis
chiral recognition mechanism
Acesso em linha:http://www.mdpi.com/1422-0067/13/1/710/
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