Targeting MAGE-C1/CT7 Expression Increases Cell Sensitivity to the Proteasome Inhibitor Bortezomib in Multiple Myeloma Cell Lines

The MAGE-C1/CT7 encodes a cancer/testis antigen (CTA), is located on the chromosomal region Xq26–27 and is highly polymorphic in humans. MAGE-C1/CT7 is frequently expressed in multiple myeloma (MM) that may be a potential target for immunotherapy in this still incurable disease. MAGEC1/CT7 expressio...

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Detalhes bibliográficos
Main Authors: de Carvalho, Fabricio, Costa, Erico T., Camargo, Anamaria A., Gregorio, Juliana C., Masotti, Cibele, Andrade, Valeria C.C., Strauss, Bryan E., Caballero, Otavia L., Atanackovic, Djordje, Colleoni, Gisele W.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218015/
https://ncbi.nlm.nih.gov/pubmed/22110734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027707
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