SNCA Triplication Parkinson's Patient's iPSC-derived DA Neurons Accumulate α-Synuclein and Are Susceptible to Oxidative Stress

Parkinson's disease (PD) is an incurable age-related neurodegenerative disorder affecting both the central and peripheral nervous systems. Although common, the etiology of PD remains poorly understood. Genetic studies infer that the disease results from a complex interaction between genetics an...

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Bibliographische Detailangaben
Hauptverfasser: Byers, Blake, Cord, Branden, Nguyen, Ha Nam, Schüle, Birgitt, Fenno, Lief, Lee, Patrick C., Deisseroth, Karl, Langston, J. William, Pera, Renee Reijo, Palmer, Theo D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217921/
https://ncbi.nlm.nih.gov/pubmed/22110584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026159
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