Heat shock protein 70/peptide complexes: potent mediators for the generation of antiviral T cells particularly with regard to low precursor frequencies

BACKGROUND: Heat shock protein 70 (HSP70) has gained major attention as an adjuvant capable of inducing antigen-specific CD8(+ )and CD4(+ )T-cell responses. The ability of HSP70/peptide complexes to elicit cytotoxic T-cell (CTL) responses by cross-presentation of exogenous antigens via HLA class I m...

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Main Authors: Tischer, Sabine, Basila, Megan, Maecker-Kolhoff, Britta, Immenschuh, Stephan, Oelke, Mathias, Blasczyk, Rainer, Eiz-Vesper, Britta
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217864/
https://ncbi.nlm.nih.gov/pubmed/21992180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-175
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