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Selective Effects of mTOR Inhibitor Sirolimus on Naïve and CMV-Specific T Cells Extending Its Applicable Range Beyond Immunosuppression

Cytomegalovirus (CMV) infection/reactivation remains among the most important complications of immunosuppression after transplantation. However, recent clinical observations indicate that mammalian target of rapamycin (mTOR) inhibition with sirolimus may improve the outcome of CMV complications. Und...

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Bibliografski detalji
Izdano u:Front Immunol
Glavni autori: Bak, Szilvia, Tischer, Sabine, Dragon, Anna, Ravens, Sarina, Pape, Lars, Koenecke, Christian, Oelke, Mathias, Blasczyk, Rainer, Maecker-Kolhoff, Britta, Eiz-Vesper, Britta
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304429/
https://ncbi.nlm.nih.gov/pubmed/30619313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02953
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