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Selective Effects of mTOR Inhibitor Sirolimus on Naïve and CMV-Specific T Cells Extending Its Applicable Range Beyond Immunosuppression

Cytomegalovirus (CMV) infection/reactivation remains among the most important complications of immunosuppression after transplantation. However, recent clinical observations indicate that mammalian target of rapamycin (mTOR) inhibition with sirolimus may improve the outcome of CMV complications. Und...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bak, Szilvia, Tischer, Sabine, Dragon, Anna, Ravens, Sarina, Pape, Lars, Koenecke, Christian, Oelke, Mathias, Blasczyk, Rainer, Maecker-Kolhoff, Britta, Eiz-Vesper, Britta
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304429/
https://ncbi.nlm.nih.gov/pubmed/30619313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02953
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