Functional PU.1 in macrophages has a pivotal role in NF-κB activation and neutrophilic lung inflammation during endotoxemia

Although the role of ETS family transcriptional factor PU.1 is well established in macrophage maturation, its role in mature macrophages with reference to sepsis- related animal model has not been elucidated. Here, we report the in vivo function of PU.1 in mediating mature macrophage inflammatory ph...

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Main Authors: Karpurapu, Manjula, Wang, Xuerong, Deng, Jing, Park, Hyesuk, Xiao, Lei, Sadikot, Ruxana T., Frey, Randall S., Maus, Ulrich A., Park, Gye Young, Scott, Edward W., Christman, John W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2011
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217408/
https://ncbi.nlm.nih.gov/pubmed/21937699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-341123
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