Overactivation of plasmacytoid dendritic cells inhibits antiviral T-cell responses: a model for HIV immunopathogenesis

A delicate balance between immunostimulatory and immunosuppressive signals mediated by dendritic cells (DCs) and other antigen-presenting cells (APCs) regulates the strength and efficacy of antiviral T-cell responses. HIV is a potent activator of plasmacytoid DCs (pDCs), and chronic pDC activation b...

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Detalhes bibliográficos
Main Authors: Boasso, Adriano, Royle, Caroline M., Doumazos, Spyridon, Aquino, Veronica N., Biasin, Mara, Piacentini, Luca, Tavano, Barbara, Fuchs, Dietmar, Mazzotta, Francesco, Lo Caputo, Sergio, Shearer, Gene M., Clerici, Mario, Graham, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217402/
https://ncbi.nlm.nih.gov/pubmed/21931112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-344218
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