Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts

Mesenchymal stromal cells (MSCs) are an essential cell type of the hematopoietic microenvironment. Concerns have been raised about the possibility that MSCs undergo malignant transformation. Several studies, including one from our own group, have shown the presence of cytogenetic abnormalities in MS...

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Bibliographische Detailangaben
Hauptverfasser: Blau, Olga, Baldus, Claudia Dorothea, Hofmann, Wolf-Karsten, Thiel, Gundula, Nolte, Florian, Burmeister, Thomas, Türkmen, Seval, Benlasfer, Ouidad, Schümann, Elke, Sindram, Annette, Molkentin, Mara, Mundlos, Stefan, Keilholz, Ulrich, Thiel, Eckhard, Blau, Igor Wolfgang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2011
Schlagworte:
Myeloid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217359/
https://ncbi.nlm.nih.gov/pubmed/21948175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-343467
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