Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts

Mesenchymal stromal cells (MSCs) are an essential cell type of the hematopoietic microenvironment. Concerns have been raised about the possibility that MSCs undergo malignant transformation. Several studies, including one from our own group, have shown the presence of cytogenetic abnormalities in MS...

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Auteurs principaux: Blau, Olga, Baldus, Claudia Dorothea, Hofmann, Wolf-Karsten, Thiel, Gundula, Nolte, Florian, Burmeister, Thomas, Türkmen, Seval, Benlasfer, Ouidad, Schümann, Elke, Sindram, Annette, Molkentin, Mara, Mundlos, Stefan, Keilholz, Ulrich, Thiel, Eckhard, Blau, Igor Wolfgang
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2011
Sujets:
Myeloid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217359/
https://ncbi.nlm.nih.gov/pubmed/21948175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-343467
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