Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation

Mir-17-92 encodes 6 miRNAs inside a single polycistronic transcript, the proper expression of which is critical for early B-cell development and lymphocyte homeostasis. However, during the T-cell antigen response, the physiologic function of endogenous miR-17-92 and the roles of the individual miRNA...

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Bibliografiske detaljer
Main Authors: Jiang, Shan, Li, Chaoran, Olive, Virginie, Lykken, Erik, Feng, Feng, Sevilla, Jose, Wan, Ying, He, Lin, Li, Qi-Jing
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2011
Fag:
Immunobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217351/
https://ncbi.nlm.nih.gov/pubmed/21972292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-355644
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