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Elucidation of mu-Opioid Gene Structure: How Genetics Can Help Predict Responses to Opioids

Opioid drugs are among the most commonly used and effective human analgesics. To date, the clinical benefits of opioid analgesics have not been fully realized due to substantial individual variations in the responses to opioids, insufficient drug dosing, and a high rate (up to 66%) of adverse events...

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Main Authors: Diatchenko, Luda, Robinson, J. Elliott, Maixner, William
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217294/
https://ncbi.nlm.nih.gov/pubmed/22102848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eujps.2011.08.022
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