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ANGPTL4 induction by prostaglandin E(2) under hypoxic conditions promotes colorectal cancer progression

Prostaglandin E(2) (PGE(2)), the most abundant COX-2–derived prostaglandin found in colorectal cancer, promotes tumor cell proliferation and survival via multiple signaling pathways. However, the role of PGE(2) in tumor hypoxia is not well understood. Here, we show a synergistic effect of PGE(2) and...

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Detalhes bibliográficos
Main Authors: Kim, Sun-Hee, Park, Yun-Yong, Kim, Sang-Wook, Lee, Ju-Seog, Wang, Dingzhi, DuBois, Raymond N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217078/
https://ncbi.nlm.nih.gov/pubmed/21937683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1262
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