Mitochondrial DNA Haplogroup Background Affects LHON, but Not Suspected LHON, in Chinese Patients

Recent studies have shown that mtDNA background could affect the clinical expression of Leber hereditary optic neuropathy (LHON). We analyzed the mitochondrial DNA (mtDNA) variation of 304 Chinese patients with m.11778G>A (sample #1) and of 843 suspected LHON patients who lack the three primary m...

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Main Authors: Zhang, A-Mei, Jia, Xiaoyun, Bi, Rui, Salas, Antonio, Li, Shiqiang, Xiao, Xueshan, Wang, Panfeng, Guo, Xiangming, Kong, Qing-Peng, Zhang, Qingjiong, Yao, Yong-Gang
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2011
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216987/
https://ncbi.nlm.nih.gov/pubmed/22110754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027750
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