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Mitochondrial DNA Haplogroup Background Affects LHON, but Not Suspected LHON, in Chinese Patients

Recent studies have shown that mtDNA background could affect the clinical expression of Leber hereditary optic neuropathy (LHON). We analyzed the mitochondrial DNA (mtDNA) variation of 304 Chinese patients with m.11778G>A (sample #1) and of 843 suspected LHON patients who lack the three primary m...

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書誌詳細
主要な著者: Zhang, A-Mei, Jia, Xiaoyun, Bi, Rui, Salas, Antonio, Li, Shiqiang, Xiao, Xueshan, Wang, Panfeng, Guo, Xiangming, Kong, Qing-Peng, Zhang, Qingjiong, Yao, Yong-Gang
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216987/
https://ncbi.nlm.nih.gov/pubmed/22110754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027750
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