Concentration-dependent Dual Effects of Hydrogen Peroxide on Insulin Signal Transduction in H4IIEC Hepatocytes

BACKGROUND: Oxidative stress induced by the accumulation of reactive oxygen species (ROS) has a causal role in the development of insulin resistance, whereas ROS themselves function as intracellular second messengers that promote insulin signal transduction. ROS can act both positively and negativel...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Iwakami, Satoshi, Misu, Hirofumi, Takeda, Takashi, Sugimori, Makoto, Matsugo, Seiichi, Kaneko, Shuichi, Takamura, Toshinari
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216925/
https://ncbi.nlm.nih.gov/pubmed/22102892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027401
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