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Fast-acting and nearly gratuitous induction of gene expression and protein depletion in Saccharomyces cerevisiae

We describe the development and characterization of a system that allows the rapid and specific induction of individual genes in the yeast Saccharomyces cerevisiae without changes in nutrients or temperature. The system is based on the chimeric transcriptional activator Gal4dbd.ER.VP16 (GEV). Upon a...

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Detalhes bibliográficos
Main Authors: McIsaac, R. Scott, Silverman, Sanford J., McClean, Megan N., Gibney, Patrick A., Macinskas, Joanna, Hickman, Mark J., Petti, Allegra A., Botstein, David
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216669/
https://ncbi.nlm.nih.gov/pubmed/21965290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-05-0466
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