Defining pathways of spindle checkpoint silencing: functional redundancy between Cdc20 ubiquitination and p31(comet)

The spindle checkpoint senses unattached or improperly attached kinetochores during mitosis, inhibits the anaphase-promoting complex or cyclosome (APC/C), and delays anaphase onset to prevent aneuploidy. The mitotic checkpoint complex (MCC) consisting of BubR1, Bub3, Mad2, and Cdc20 is a critical AP...

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Hauptverfasser: Jia, Luying, Li, Bing, Warrington, Ross T., Hao, Xing, Wang, Shixuan, Yu, Hongtao
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2011
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216649/
https://ncbi.nlm.nih.gov/pubmed/21937719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-05-0389
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