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Activation of the Aryl Hydrocarbon Receptor by TCDD Inhibits Mammary Tumor Metastasis in a Syngeneic Mouse Model of Breast Cancer

Treatment with aryl hydrocarbon receptor (AhR) agonists can slow or reverse the growth of primary mammary tumors in rodents, which has fostered interest in developing selective AhR modulators for treatment of breast cancer. However, the major goal of breast cancer therapy is to inhibit metastasis, t...

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Detalhes bibliográficos
Main Authors: Wang, Tao, Wyrick, Katie L., Meadows, Gary G., Wills, Tamara B., Vorderstrasse, Beth A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216416/
https://ncbi.nlm.nih.gov/pubmed/21948867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr247
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