Sensitized Splenocytes Result in Deleterious Cytokine Cascade and Hyperinflammatory Response in Rats with Pneumocystis Pneumonia despite the Presence of Corticosteroids

The immune response to the opportunistic pulmonary pathogen Pneumocystis can have beneficial and harmful effects on the host despite the presence of corticosteroids. We hypothesized that this deleterious hyperinflammatory response is associated with exaggerated cytokine production. The adoptive tran...

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Detalhes bibliográficos
Main Authors: Thullen, Timothy D., Ashbaugh, Alan D., Daly, Kieran R., Linke, Michael J., Steele, Paul E., Walzer, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321630/
https://ncbi.nlm.nih.gov/pubmed/14742518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.757-765.2004
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