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Characterisation and internalisation of recombinant humanised HMFG-1 antibodies against MUC1
The humanised HMFG-1 immunoglobulin has been extensively developed as a clinical immunotherapeutic agent for MUC1 expressing tumours. We have constructed a single-chain Fv (scFv) and Fab fragment from this antibody and shown that both these species retain their specificity for MUC1. The scFv was les...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3216111/ https://ncbi.nlm.nih.gov/pubmed/16265351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602847 |
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