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Characterisation of a humanised bispecific monoclonal antibody for cancer therapy.

A humanised bispecific monoclonal antibody (bsMAb) with binding specificity for carcinoembryonic antigen (CEA) on one arm and a radiolabelled chelate (DTPA-90Y) on the other arm was generated by consecutively transfecting the humanised genes of an anti-CEA MAb and the chimerised genes of an anti-che...

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Detalles Bibliográficos
Autores principales: Bruynck, A., Seemann, G., Bosslet, K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1993
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968282/
https://ncbi.nlm.nih.gov/pubmed/8439495
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