Generation of bispecific monoclonal antibodies for two phase radioimmunotherapy.

A two phase radioimmunotherapy based on bispecific MAbs in which one arm recognises a tumour antigen and the other a radiolabelled chelate, may prove more effective in the treatment of carcinomas than currently available immunotherapies. To establish this system we first showed that penetration into...

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Main Authors: Bosslet, K., Steinstraesser, A., Hermentin, P., Kuhlmann, L., Bruynck, A., Magerstaedt, M., Seemann, G., Schwarz, A., Sedlacek, H. H.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1972387/
https://ncbi.nlm.nih.gov/pubmed/2039692
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