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Systemic Th1 Immunization of Mice against Helicobacter pylori Infection with CpG Oligodeoxynucleotides as Adjuvants Does Not Protect from Infection but Enhances Gastritis

Recent reports have suggested that oral vaccination of mice against Helicobacter pylori is dependent on a Th1-mediated immune response. However, oral vaccination in mice neither induces sterilizing immunity nor leads to complete protection from disease. Therefore, in this study we investigated wheth...

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Bibliografiske detaljer
Main Authors: Sommer, Frank, Wilken, Henning, Faller, Gerhard, Lohoff, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC321611/
https://ncbi.nlm.nih.gov/pubmed/14742550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.1029-1035.2004
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