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Systemic Th1 Immunization of Mice against Helicobacter pylori Infection with CpG Oligodeoxynucleotides as Adjuvants Does Not Protect from Infection but Enhances Gastritis

Recent reports have suggested that oral vaccination of mice against Helicobacter pylori is dependent on a Th1-mediated immune response. However, oral vaccination in mice neither induces sterilizing immunity nor leads to complete protection from disease. Therefore, in this study we investigated wheth...

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Detalhes bibliográficos
Main Authors: Sommer, Frank, Wilken, Henning, Faller, Gerhard, Lohoff, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321611/
https://ncbi.nlm.nih.gov/pubmed/14742550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.1029-1035.2004
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