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Systemic Th1 Immunization of Mice against Helicobacter pylori Infection with CpG Oligodeoxynucleotides as Adjuvants Does Not Protect from Infection but Enhances Gastritis

Recent reports have suggested that oral vaccination of mice against Helicobacter pylori is dependent on a Th1-mediated immune response. However, oral vaccination in mice neither induces sterilizing immunity nor leads to complete protection from disease. Therefore, in this study we investigated wheth...

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Autors principals: Sommer, Frank, Wilken, Henning, Faller, Gerhard, Lohoff, Michael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC321611/
https://ncbi.nlm.nih.gov/pubmed/14742550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.1029-1035.2004
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