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H3K27 Demethylase UTX-1 Regulates C. elegans Lifespan in a Germline-Independent, Insulin-Dependent, Manner

Aging is accompanied by alterations in epigenetic marks that control chromatin states, including histone acetylation and methylation. Enzymes that reversibly affect histone marks associated with active chromatin have recently been found to regulate aging in C. elegans. However, relatively little is...

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Autors principals: Maures, Travis J., Greer, Eric L., Hauswirth, Anna G., Brunet, Anne
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215905/
https://ncbi.nlm.nih.gov/pubmed/21834846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00738.x
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