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The C. elegans H3K27 Demethylase UTX-1 Is Essential for Normal Development, Independent of Its Enzymatic Activity

Epigenetic modifications influence gene expression and provide a unique mechanism for fine-tuning cellular differentiation and development in multicellular organisms. Here we report on the biological functions of UTX-1, the Caenorhabditis elegans homologue of mammalian UTX, a histone demethylase spe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vandamme, Julien, Lettier, Gaëlle, Sidoli, Simone, Di Schiavi, Elia, Nørregaard Jensen, Ole, Salcini, Anna Elisabetta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342935/
https://ncbi.nlm.nih.gov/pubmed/22570628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002647
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