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The C. elegans H3K27 Demethylase UTX-1 Is Essential for Normal Development, Independent of Its Enzymatic Activity
Epigenetic modifications influence gene expression and provide a unique mechanism for fine-tuning cellular differentiation and development in multicellular organisms. Here we report on the biological functions of UTX-1, the Caenorhabditis elegans homologue of mammalian UTX, a histone demethylase spe...
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Hauptverfasser: | , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Public Library of Science
2012
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3342935/ https://ncbi.nlm.nih.gov/pubmed/22570628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002647 |
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